Awesome! All the key details on NMN’s safety and reliability are included here！
Many users are still confused about the sales qualifications of UndoAge’s NMN. Today’s article will clear up your doubts and help you understand NMN in a more objective and scientific way.
For many people, their first impression of NMN comes from marketing terms like “anti-aging pill,” “longevity drug,” or even “elixir of life.”
And the reason more people began to question NMN was that the U.S. FDA announced restrictions on it, prohibiting its use as a dietary supplement ingredient. Following this decision, several e-commerce platforms began removing NMN-related products.
The prohibition notice issued by Amazon to its sellers
However, it’s important to note that NMN has been studied for nearly a decade since its anti-aging benefits were first discovered, with strong scientific evidence supporting its efficacy. In this sense, the FDA’s move can also be viewed as an effort to regulate excessive market hype rather than a denial of NMN’s scientific value.
In fact, from a scientific perspective, NMN — as a precursor of NAD+ — can be highly effective when supplemented in targeted and appropriate amounts, especially for individuals with naturally low NAD+ levels. Previous human clinical studies have shown that taking NMN can improve several key health indicators and enhance muscle strength.
Stricter oversight will ultimately help protect the interests of consumers who take NMN over the long term, ensuring that products available on the market meet higher standards of quality and safety.
In the long run, this move may encourage a more transparent and standardized industry, where only compliant and well-regulated brands are allowed to sell NMN products.
01 Key Driver of NMN: Insights from Biological Research
The background behind FDA’s decision is quite complex. Research on NAD+, a molecule that plays a key role in cellular aging, has been progressing rapidly in recent years. Some biotechnology companies have been working to develop NAD+ enhancers as prescription drugs for conditions related to mitochondrial function and aging.
However, drug approval is a long process that requires multiple stages of clinical trials before FDA authorization, while at the same time the supplement market for “NAD+ precursors” has grown extremely fast and even overheated.
As a result, certain research institutions and companies submitted formal letters to the FDA, urging the agency to remove NMN supplements from the market. Many observers see this action as driven by regulatory and commercial considerations, rather than as a scientific denial of NMN’s benefits.
Open letter
It’s also worth noting that many researchers who study NAD+ have personally spoken about the potential of NMN and have continued to take it themselves for years, often sharing their experiences in interviews or public talks.
02 NMN Is Innocent: A Look into the Commercial Reasons Behind the Ban
There is a commercial reason behind the FDA’s ban on NMN. One biotechnology company intended to develop NMN into a new drug (MIB-626), but in the United States, the approval process for a new drug is very lengthy.
Meanwhile, other companies began selling NMN in dietary supplements, which do not require FDA approval.
The biotechnology company naturally did not want others to take the lead and benefit commercially, so they requested that the FDA consider NMN — as an ingredient under investigation for drug development — unsuitable for use in supplements. As a result, in early 2024, the FDA issued new regulations prohibiting all NMN-containing dietary supplements.
This action was in line with U.S. law, which states that an ingredient already under investigation as a drug cannot be marketed as a dietary supplement.
Understanding the timeline of this event actually highlights the effectiveness of NMN as an ingredient, which may also be used in pharmaceuticals in the future.
The current NMN market is mixed, with many substandard products, so it is essential for consumers to carefully select products that are legitimate and capable of synthesizing NAD+.
When choosing NMN supplements, consumers should focus on two key factors: the manufacturer and the raw material supplier.
Experienced users have also noticed that many NMN products on the market are simply branded without being produced in-house, instead relying on contract manufacturers. The choice of raw material supplier is equally important, as NMN can be synthesized in different ways.
Regarding the so-called “ban battle” over NMN, there has been an important update in September this year:
On September 29, 2025, the Natural Products Association (NPA) announced on its official website that the U.S. Food and Drug Administration (FDA) has officially confirmed that β-Nicotinamide Mononucleotide (NMN) can be legally used in dietary supplements. This decision ended nearly three years of regulatory controversy over NMN, completely reversing the FDA’s previous ban, and provided crucial policy clarity for the global NMN industry.
Major companies in the industry are likely to re-engage with the market and expand their NMN offerings. Overall, NMN supporters are celebrating this milestone, viewing it as a turning point that brings stability and growth potential to the dietary supplement industry.
03 Tracing the Origin of UndoAge’s NMN
By interpreting relevant regulations, we are reminded to be vigilant when purchasing NMN products and choose those with clear origins and guaranteed quality.
Following the principle of “buy the right one, not the expensive one” ensures our health and safety.
As consumers, we must learn to understand the policies and make informed choices.
When selecting NMN, it’s essential to check whether the raw material supplier truly exists and complies with local regulations, whether the manufacturing factory is qualified, and which extraction method is used—fermentation, full enzymatic synthesis, or the least efficient partial enzymatic process. Only NMN products that we fully understand and trust are the ones we can take with confidence over the long term.
UndoAge’s NMN demonstrates both safety and reliability, making it a trustworthy choice for consumers. As of now, UndoAge NMN has sold over 1,000,000 capsules.
First, UndoAge’s NMN is sourced from Hong Kong, which is not included in the restricted regions. NMN products from other reputable supplement brands are still available on major platforms.
Second, UndoAge’s NMN raw material supplier, Bontac, is a leading global NMN supplier, providing high-quality research-grade NMN for scientific studies and academic institutions worldwide.
Image source: Screenshot from Bontac’s official website
Finally, UndoAge’s NMN is manufactured at Wright Life®, a factory that has obtained five major international certifications.
Wright Life® is a leading health supplement manufacturer in Hong Kong, with its own brands sold on major e-commerce platforms and multiple offline stores throughout Hong Kong.
UndoAge chooses to collaborate with established and reputable manufacturers and organizations to ensure consumer trust and peace of mind.
Research on NMN’s anti-aging effects and its potential in human clinical applications is continuing to expand. A study published in the journal MedComm revealed that nicotinamide mononucleotide (NMN), as a promising intervention, can significantly improve ovarian mitochondrial function and energy metabolism in aging mice, reduce ovarian inflammation, and thereby enhance ovarian health and ovarian reserve.
Nicotinamide adenine dinucleotide (NAD+) is a key cofactor within cells, widely involved in regulating energy metabolism, oxidative stress, and inflammatory responses. As the saying goes, NAD+ levels naturally decline with age, which is closely associated with many age-related issues.
Nicotinamide mononucleotide (NMN), as a precursor of NAD+, can effectively increase NAD+ levels in the body and help slow down ovarian aging, offering a new approach to addressing this challenge. It is expected that future research will provide more evidence-based studies to support NMN’s application in human anti-aging and longevity.
Reference:
[1]https://onlinelibrary.wiley.com/doi/10.1002/mco2.727